Gang intervention during COVID-19: A qualitative study of multidisciplinary teams and street outreach in Denver.

Gang and violence intervention programs have become a staple in American cities. These programs often find themselves navigating turbulent political environments, a challenge that can be exacerbated during times of societal upheaval, such as the COVID-19 pandemic. The current study examines how the pandemic impacted the forms and functions of the Gang Reduction Initiative of Denver (GRID). While GRID coordinates many strategies and collaborates with government and community groups across Denver, its centerpiece intervention entails multidisciplinary teams and street outreach, the focus of this qualitative study. We draw on 197  hours of field-based observation and 19 semi-structured interviews gathered as part of an evaluation of this intervention-initiated prior to the pandemic-to arrive at three key conclusions on the impact of COVID-19. First, upper-level administrative support can be a critical factor in agency efficacy and morale. City government's tenuous familiarity and ties with GRID was consequential to non-essential classification at the early stage of the pandemic. Second, agency leaders are crucial advocates for their agency, as GRID navigated many challenges without stable leadership and suffered as a result. Finally, interagency collaboration and relationships are slow to develop and easy to lose, made even more fragile in times of crisis. We discuss these findings in the context of large-scale federal investment in community violence intervention.

The challenge of community mental health interventions with patients, relatives, and health professionals during the COVID-19 pandemic: a real-world 9-month follow-up study.

Since the beginning of the COVID-19 pandemic, the need to implement protocols that respond to the mental health demands of the population has been demonstrated. The PASMICOR programme started in March 2020, involving a total of 210 requests for treatment. Out of those subjects, the intervention was performed in 53 patients with COVID-19 without history of past psychiatric illness, 57 relatives and 60 health professionals, all of them within the area of Salamanca (Spain). Interventions were carried out by professionals of the public mental health service mostly by telephone. Depending on clinical severity, patients received basic (level I) or complex psychotherapeutic care combined with psychiatric care (level II). The majority of attended subjects were women (76.5%). Anxious-depressive symptoms were predominant, although sadness was more frequent in patients, insomnia in relatives and anxiety and fear in health professionals. 80% of the sample, particularly most of the health professionals, required a high-intensity intervention (level II). Nearly 50% of the people treated were discharged after an average of 5 interventions. Providing early care to COVID-19 patients, relatives and professionals by using community mental health resources can help to reduce the negative impact of crises, such as the pandemic, on the most affected population groups.

Acceptability of the Vaccine against COVID-19 in Spanish Health Sciences Students: A Cross-Sectional Study.

Healthcare professionals must play an exemplary role in the field of vaccinology. It is convenient that they are trained during their time at university. The objective of this study was to determine the acceptability of the vaccines against COVID-19 in health sciences students in Spanish universities. A cross-sectional study was performed regarding the acceptance of the vaccines against COVID-19 in students in the Health Sciences Degrees in Spanish universities was performed on a sample of students of nursing, medicine, and pharmacy during the spring of 2021, via an online questionnaire with 36 questions designed ad hoc, self-administered, anonymized, and standardized. There were 1222 students participating, of Spanish nationality (97.4%), women (80.5%) and with an average age of 22.0 ± 4.8 years old. Of those, 12.3% had had the disease, 44.0% had to quarantine, 70.8% had undergone diagnostic tests, out of which 14.1% were positive. In total, 97.5% of those surveyed indicated their desire of being vaccinated, if possible, with Comirnaty® (74.9%). At the time of the study, 49.6% were already vaccinated. The reasons for vaccination differed according to the degree and the doubts about vaccine safety was the largest reason for reluctance. Some 37.7% suspected that there are unknown adverse effects and 85.6% of those vaccinated experienced some mild effects after injection. Vaccine acceptance and confidence in the recommendations given by health authorities is high in health sciences students.

An Experimental Model of Neuro-Immune Interactions in the Eye: Corneal Sensory Nerves and Resident Dendritic Cells.

The cornea is an avascular connective tissue that is crucial, not only as the primary barrier of the eye but also as a proper transparent refractive structure. Corneal transparency is necessary for vision and is the result of several factors, including its highly organized structure, the physiology of its few cellular components, the lack of myelinated nerves (although it is extremely innervated), the tightly controlled hydration state, and the absence of blood and lymphatic vessels in healthy conditions, among others. The avascular, immune-privileged tissue of the cornea is an ideal model to study the interactions between its well-characterized and dense sensory nerves (easily accessible for both focal electrophysiological recording and morphological studies) and the low number of resident immune cell types, distinguished from those cells migrating from blood vessels. This paper presents an overview of the corneal structure and innervation, the resident dendritic cell (DC) subpopulations present in the cornea, their distribution in relation to corneal nerves, and their role in ocular inflammatory diseases. A mouse model in which sensory axons are constitutively labeled with tdTomato and DCs with green fluorescent protein (GFP) allows further analysis of the neuro-immune crosstalk under inflammatory and steady-state conditions of the eye.

The Spanish home care workers between job vulnerability and happiness in times of crisis

Purpose>This study aims to analyze the well-being experience of home care workers regardless of the service management model. It also aims to analyze their emotional experiences of their activity and working conditions.Design/methodology/approach>This study, using a mixed qualitative and quantitative analysis, allows a combined analysis for a better understanding of the well-being experience of home care workers.Findings>Home care workers experience intrinsic job satisfaction and demonstrate this with positive emotions regardless of their work situation.Practical implications>Caring for the carer should be a business value. Measures oriented toward workers’ comfort generate greater happiness and commitment, which is automatically transferred to the quality of the care provided and reduces the psychosocial risks of their professional activity.Social implications>Visualizing the social reality of an essential profession through research generates verifiable evidence that will help to improve the working conditions of home care workers in Spain.Originality/value>To the best of the authors’ knowledge, this pioneering study in Spain introduces a greater understanding of how home care workers in Spain experience their work reality.

Detection of Neutralizing Antibodies against SARS-CoV-2 Post-Vaccination in Health Care Workers of a Large Tertiary Hospital in Spain by Using a Rapid Test LFIC and sVNT-ELISA.

The presence of neutralizing antibodies (NAbs) against SARS-CoV-2 represent a surrogate marker of immunologic protection in populations at high risk of infection such as healthcare workers caring for hospitalized patients with COVID-19. As recommended by CDC and the European CDC, the use of rapid diagnostic tests during population-based evaluations offers an opportunity to identify individuals with serologic evidence of natural infection or who have undergone vaccination. We carried out a cross-sectional study to assess the presence of neutralizing antibodies against SARS-CoV-2 among medical providers at an intensive care unit of a large referral hospital in Alicante, Spain. In addition, we tested for the presence of neutralizing antibodies compared to serum of uninfected individuals from a Biobank. We were also interested in evaluating the use of a rapid lateral flow immunochromatography (LFIC) test against a surrogate ELISA viral neutralization test (sVNT). This rapid test demonstrated a specificity of 1.000 95% CI (0.91-1.00) and the sensitivity of 0.987 95% CI (0.93-1.00). The negative predictive value was 95%. After six months, this rapid test demonstrated that those immunized with two doses of BioNTech/Pfizer vaccine, maintained optimal levels of neutralizing antibodies. We concluded that all Health Care Workers develop NAbs and the use of this rapid immunochromatographic test represents a potential tool to be used in population-based studies to detect serological antibody responses to vaccination. Vaccination policies could benefit from this tool to assess additional doses of vaccine or boosters among high-risk populations.

The Impact of the SARS-CoV-2 Pandemic on the Emergency Department and Management of the Pediatric Asthmatic Patient.

INTRODUCTION: Asthma exacerbation is among the commonest causes for pediatric emergency room visits, and respiratory viruses are frequent triggers of such exacerbations. Few studies have evaluated the consequences of the novel human coronavirus that causes the illness currently known as COVID-19, in the pediatric population. PURPOSE: The objective of this study was to analyze the impact of the COVID-19 pandemic and lockdown measures on the emergency department in the pediatric asthmatic patient. PATIENTS AND METHODS: This retrospective observational study evaluated pediatric patients treated at the Pediatric Emergency Service for wheezing episodes. Changes in the number and characteristics of these patients over the same period of 2019 as compared to 2020 during the month following the alarm declaration (March 14 to April 15) were evaluated. RESULTS: In total, data of 30 asthma patients managed in the period after the declaration of the coronavirus pandemic and of 158 asthma patients managed in the pre-COVID-19 period were included. In 2020, patient visits decreased by 82% in 2019. No statistically significant differences among age, sex, oxygen saturation, fever status, or number of severe bronchospasm episodes were found. Nebulized medication usage was reduced significantly since the alarm declaration. No significant increase in requests for complementary testing in the COVID-19 period was found. No patient requiring hospital admission was found to be PCR SARS-CoV-2 positive. Median time spent in the emergency department decreased from 180 minutes in 2019 to 85 minutes in the COVID-19 era. CONCLUSION: The COVID-19 pandemic and ensuing lockdown measures have led to an extraordinary reduction in emergency visits to the pediatric service. The ongoing pandemic has also led to improvements in the approach to asthma exacerbations and wheezing, to reduce the risk of exposure to the virus, such as increased use of pressurized metered dose inhaler and decreased time in the Emergency Department.

Cross-sectional analysis of coping strategies and anxiety and depression levels in a sample of the Andalusian population during the home lockdown caused by the COVID-19 pandemic

The restrictive measures put into place to control the COVID-19 pandemic in 2020 have prompted the need to study the possible health impacts in the middle term. Deprivation of the fundamental right to mobility results in an increase in affective disorders and the risks that they entail for the population. The goal of this study is to examine anxiety and depression levels during the first national lockdown and to determine the key coping strategies in order to develop health treatment and promotion programmes. The sample, comprised of 485 participants (mean age = 40) from Andalusia, received questionnaires via email between March and June. The results showed that acceptance, active coping and humour were the most effective coping strategies to explain and predict a decrease in anxiety and depression within the context of the home lockdown. Therefore, we recommend that these coping strategies be studied in order to develop programmes that help prevent the psychological consequences of the lockdown. (PsycInfo Database Record (c) 2022 APA, all rights reserved) (Spanish) Las medidas restrictivas puestas en marcha para el control de la pandemia de COVID-19 en el ano 2020, han provocado la necesidad de estudiar los posibles impactos para la salud a medio plazo. La privacion del derecho fundamental a la movilidad tiene como consecuencia el aumento de los trastornos afectivos y el riesgo que estos implican para la poblacion. El presente estudio tiene por objetivo estudiar los niveles de ansiedad y depresion durante el primer confinamiento nacional y determinar las estrategias de afrontamiento claves para el desarrollo de programas de intervencion y promocion de la salud. La muestra, compuesta por 485 participantes (edad media = 40 anos) procedentes de Andalucia, recibio los cuestionarios a traves de correo electronico entre los meses de marzo y junio. Los resultados muestran que la aceptacion, el afrontamiento activo y el humour han sido las estrategias de afrontamiento mas eficaces para explicar y predecir la disminucion de la ansiedad y la depresion en el contexto del confinamiento domiciliario. Por ello, recomendamos que estas estrategias de afrontamiento sean estudiadas para el desarrollo de programas que permitan prevenir las consecuencias psicologicas derivadas del confinamiento. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

Impact on Sleep Quality, Mood, Anxiety, and Personal Satisfaction of Doctors Assigned to COVID-19 Units.

The SARS-CoV-2 health emergency has led to a restructuring of health care systems and the reassignment of medical specialists from their usual duties to attend COVID-19 patients. The aim of this paper is to describe the levels of insomnia, anxiety, depression, and the impact on quality of life of doctors who were on the frontline of COVID-19 during the first two waves of the pandemic. Self-report surveys were conducted on said physicians during both waves, with 83 and 61 responses in the first and second waves, respectively. The reported presence of insomnia was frequent (71.8%), although it decreased in the second survey. Anxiety was moderate, decreasing from 57.1% to 43.1% between measurements. Overall, depression rates decreased between the two surveys. Substance use was found to have an indirect correlation with personal and professional satisfaction. In the light of the unforeseeable evolution of the pandemic and the medium- to long-term repercussions on professionals, we believe the adaptation of health resources is crucial to meet the new unpredictable mental health needs of this group.

Assessment of Spanish Food Consumption Patterns during COVID-19 Home Confinement.

People's eating habits and lifestyle can have a negative impact on health. In situations of difficulty or socioeconomic crisis, these habits tend to be modified, leading to unhealthy dietary patterns that result in an increase of chronic non-communicable diseases (NCDs). Previous studies have indicated that, due to the state of alarm imposed in Spain to combat the spread of COVID-19, an increase in the purchase of non-core products occurred, along with a decrease in the daily physical activity of the population. This could be a risk factor for COVID-19 infection. The objective of this observational study was to analyze the dietary pattern of the Spanish population during home confinement and to compare it with the pattern of habitual consumption collected in the last National Health Survey, analyzing the possible changes. More than half of the respondents in the sample increased their consumption of sweets and snacks during confinement, while the consumption of fresh products decreased. Most claimed to be emotionally hungry, leading to an increase in their daily energy intake. The stress and anxiety generated by confinement could be the cause of the increased consumption of products rich in sugars and saturated fats, which are associated with greater stress and anxiety.

ENTREPRENEUR HAPPINESS AS A PORTFOLIO OF COMPETITIVENESS AND SUSTAINABILITY IN THE COVID-19 ERA

[...]the need to empirically study the cause-effect relationship exerted by socio-demographic, economic, cultural or political variables on the happiness of entrepreneurs (Ravina-Ripoll et al., 2020). [...]the difficulty of considering the happiness of this human capital as an element that facilitates the creation of innovative and high-quality products or services (Lee, 2019). What factors lead people to be happy entrepreneurs, does the type of business activity that an entrepreneur carries out have an impact on their level of subjective well-being, does the entrepreneurial spirit of individuals have its origin in improving their status quo of psychological and economic happiness, and how can the creation of social value generated by happy entrepreneurs be measured? JUSTIFICATION As is well known, the multidimensional study of the concept of entrepreneurship basically involves the disciplines of sociology, business organization and psychology.

Intersection of Data Science and Smart Destinations: A Systematic Review.

This systematic review adopts a formal and structured approach to review the intersection of data science and smart tourism destinations in terms of components found in previous research. The study period corresponds to 1995-2021 focusing the analysis mainly on the last years (2015-2021), identifying and characterizing the current trends on this research topic. The review comprises documentary research based on bibliometric and conceptual analysis, using the VOSviewer and SciMAT software to analyze articles from the Web of Science database. There is growing interest in this research topic, with more than 300 articles published annually. Data science technologies on which current smart destinations research is based include big data, smart data, data analytics, social media, cloud computing, the internet of things (IoT), smart card data, geographic information system (GIS) technologies, open data, artificial intelligence, and machine learning. Critical research areas for data science techniques and technologies in smart destinations are public tourism marketing, mobility-accessibility, and sustainability. Data analysis techniques and technologies face unprecedented challenges and opportunities post-coronavirus disease-2019 (COVID-19) to build on the huge amount of data and a new tourism model that is more sustainable, smarter, and safer than those previously implemented.

Confinement Situation of the Spanish Population during the Health Crisis of COVID-19: Resilience Mediation Process in the Relationship of Dispositional Optimism and Psychological Well-Being.

The pandemic generated by COVID-19 is one of the most complex challenges humanity has faced in recent years. This study aims to explore the levels of dispositional optimism, resilience and psychological well-being in the sociodemographic and economic situation produced during the state of alarm and to investigate the resilience mediation between optimism and psychological well-being. The sample included 566 volunteers from Spain (73.5% women; M = 40.2 years, SD = 12.8). An ad hoc questionnaire was applied to request socioeconomic data and dispositional optimism (LOT-R). Resilience and psychological well-being were, respectively, evaluated by the Ryff scale and the Wagnild and Young scale. The results show that older and people with higher educational levels are more optimistic and have better psychological well-being. Well-being is also greater in married, divorced and widowed people and in those who have lived in outdoor spaces. However, those with spaced housing were more optimistic. Finally, it was found that the most optimistic people have better psychological well-being and that this is increased by the mediation process exercised by the ability to overcome adversity, provided age and educational level are controlled. It can be concluded that the design of preventive programs focused on improving strengths, positive emotions and skills in the population would be convenient to protect mental health.

Seroprevalence Study and Cross-Sectional Survey on COVID-19 for a Plan to Reopen the University of Alicante (Spain).

The implementation of strategies to mitigate possible cases of COVID-19 were addressed at the University of Alicante for the safe reopening of the 2020/2021 academic year. To discover the prevalence of immunity against SARS-CoV-2, a study was designed using a rapid immunoassay test (carried out between 6 and 22 July 2020), and in addition a cross-sectional survey was conducted on risk factors, symptoms, predisposition for becoming vaccinated, and sources of information about COVID-19. A random sample, stratified by students, faculty, and administrative staff, was selected. The seroprevalence found was 2.64% (39/1479; 95% CI 1.8-3.4), and the adjusted seroprevalence was 2.89% (95% CI 2.1-3.7). The average age of the students was 23.2 years old, and 47.6 years old for staff. In relation to COVID-19, the following was found: 17.7% pauci-symptomatic, 1.3% symptomatic, 5.5% contact with cases, 4.9% confined, and 0.3% PCR positive. More than 90% complied with preventive measures. The proportion willing to receive the COVID-19 vaccine was 91%. Their sources of information were the Internet (74%) and television (70.1%). They requested that the university offer information (45.1%), training (27%), and provide Personal Protective Equipment (PPE) (26.3%). Lastly, 87.9% would repeat the test. A plan was established that included the follow-up of cases and contacts, random sample testing, training courses, bimodal teaching, a specific website, and the distribution of PPE.

Impact of COVID-19 Confinement on Physical Activity and Sedentary Behaviour in Spanish University Students: Role of Gender.

During the COVID-19 pandemic, entire populations were instructed to live in home-confinement to prevent the expansion of the disease. Spain was one of the countries with the strictest conditions, as outdoor physical activity was banned for nearly two months. This study aimed to analyse the changes in physical activity and sedentary behaviours in Spanish university students before and during the confinement by COVID-19 with special focus on gender. We also analysed enjoyment, the tools used and motivation and impediments for doing physical activity. An online questionnaire, which included the International Physical Activity Questionnaire Short Form and certain "ad hoc" questions, was designed. Students were recruited by distributing an invitation through the administrative channels of 16 universities and a total of 13,754 valid surveys were collected. Overall, university students reduced moderate (-29.5%) and vigorous (-18.3%) physical activity during the confinement and increased sedentary time (+52.7%). However, they spent more time on high intensity interval training (HIIT) (+18.2%) and mind-body activities (e.g., yoga) (+80.0%). Adaptation to the confinement, in terms of physical activity, was handled better by women than by men. These results will help design strategies for each gender to promote physical activity and reduce sedentary behaviour during confinement periods.

In Memoriam: A Memoir for Our Fallen "Heroes".

Even though neurosurgeons exercise these enormous and versatile skills, the COVID-19 pandemic has shaken the fabrics of the global neurosurgical family, jeopardizing human lives, and forcing the entire world to be locked down. We stand on the shoulders of the giants and will not forget their examples and their teachings. We will work to the best of our ability to honor their memory. Professor Harvey Cushing said: "When to take great risks; when to withdraw in the face of unexpected difficulties; whether to force an attempted enucleation of a pathologically favorable tumor to its completion with the prospect of an operative fatality, or to abandon the procedure short of completeness with the certainty that after months or years even greater risks may have to be faced at a subsequent session-all these require surgical judgment which is a matter of long experience." It is up to us, therefore, to keep on the noble path that we have decided to undertake, to accumulate the surgical experience that these icons have shown us, the fruit of sacrifice and obstinacy. Our tribute goes to them; we will always remember their excellent work and their brilliant careers that will continue to enlighten all of us.

Early Report on the Impact of COVID-19 Outbreak in Neurosurgical Practice Among Members of the Latin American Federation of Neurosurgical Societies.

BACKGROUND: The COVID-19 pandemic has caused severe economic consequences by local governmental measures to contain the outbreak. We provide insight on the impact that health care restriction has made on neurosurgical activity in Latin Iberoamerica. METHODS: We performed an internet-based survey among presidents and members of the societies of the Latin American Federation of Neurosurgical Societies (FLANC). We blindly analyzed information regarding local conditions and their impact on neurosurgical praxis using SPSS software. RESULTS: Information came from 21 countries. Sixteen society presidents reported having suspended regular activities and deferring local scheduled congresses, 14 reported mandatory isolation by government, and 4 instituted a telemedicine project. Four-hundred eighty-six colleagues, mean age 49 years, reported a mean 79% reduction in their neurosurgical praxis. Seventy-six percent of neurosurgeons have savings to self-support for 3-6 months if restrictions are long lasting. CONCLUSIONS: Stopping activities among societies of the FLANC, together with a drop of 79% of neurosurgical praxis, adds to deficits in provider's protection equipment and increasing demand for attention in the health care systems, representing a huge financial risk to their sustainability. Neurosurgeons should be involved in local policies to protect health and economy. Telemedicine represents an excellent solution, avoiding another pandemic of severe diseases across all-specialties as nonessential care can turn essential if left untreated. Financial support and ethics code review is needed to battle this new disease, designated the occupational disease of the decade, that continues to scrag the health care system. Times of crisis are times of great opportunities for humanity to evolve.